The discovery of a special compound in red wine paved the way for the development of new natural anti-depressant and anxiety medicines.
Previously there have been many studies on the benefits of red wine, including strengthening the immune system, increasing bone density, preventing obesity. Recently, however, some new effects of red wine are known, such as anti-stress and depression.
Specifically, resveratrol in red wine is mainly responsible for these beneficial effects on the human body.
According to researchers at the University of Buffalo and Xuzhou Medical University in China, resveratrol helps prevent the expression of an enzyme involved in controlling stress levels in the brain.
The study’s co-author Ying Xu said that its effect is so powerful that it can completely replace effective drugs for depression and anxiety disorders.
Resveratrol is found mainly in grape skins and seeds along with berries. This is also a compound that many people claim to have good anti-aging ability and disease.
This is not the first time, resveratrol’s antidepressant and anxiety effects have been discovered. Earlier a study found that resveratrol acts on the enzyme phosphodiesterase 4 (PDE4), an enzyme controlled by the corticosterone hormone.
However, scientists have not been able to find a way to explain this relationship. In a study on rats, Xu and his team found that PDE4 causes behavior like anxiety and depression.
Corticosterone is the main hormone responsible for body reactions to stress. Excessive compression of the body can boost the amount of corticosterone hormone. Gradually this condition will lead to depression or other mental disorders.
Most common depression treatments today use serotonin. This therapy is sometimes ineffective because only one-third of depressed patients relieve symptoms.
During the analysis of the results, the team found that resveratrol inhibited the expression of PDE4, thereby helping to protect the corticosterone nervous system. This is an important finding because it could pave the way for the production of a new natural antidepressant.
The study is published in the recent issue of Neuropharmacology.